分类: PGT Guides

  • PGT-A vs PGT-M vs PGT-SR: a patient-friendly guide

    PGT is not one test and it is not automatically part of every IVF cycle. The right conversation begins with a specific clinical question, informed consent and a clear understanding of possible results.

    The three terms in plain English

    PGT-A provides information about chromosome number in sampled embryo cells. PGT-M is designed around a known single-gene condition. PGT-SR may be used when a parent carries a structural chromosome rearrangement.

    • PGT-A: chromosome-number screening
    • PGT-M: a known monogenic condition
    • PGT-SR: a documented structural rearrangement

    Why testing is not a guarantee

    An embryo result cannot guarantee implantation, pregnancy, live birth or the health of a future child. Sampling, laboratory limits, mosaic findings and the many non-genetic factors involved in pregnancy all matter.

    Patients should ask how the clinic reports mosaic or no-result findings, whether genetic counselling is available and what confirmatory prenatal testing may later be discussed.

    Questions for your consultation

    A useful consultation should connect the proposed test to your history—not simply add it to a package.

    • What clinical question are we trying to answer?
    • What are the alternatives, including not testing?
    • What results might the laboratory report?
    • How will abnormal, mosaic or no-result findings be managed?
    • Will a genetic counsellor review our case?
  • IVF in Thailand: a realistic timeline for international patients

    International IVF is easier to plan when the clinical timeline and the travel timeline are separated. Your exact schedule depends on your protocol, response and clinic, but the planning stages are predictable.

    Before travel

    The clinic first reviews your medical and fertility history, recent ovarian-reserve testing, ultrasound information, semen analysis and any genetic reports. Some baseline monitoring may be completed locally if the treating clinic agrees.

    • Remote doctor review
    • Written protocol and medication plan
    • Local monitoring agreement
    • Visa, flight and accommodation buffer

    The Bangkok treatment window

    Ovarian stimulation commonly requires repeated monitoring before egg retrieval. The calendar can shift because follicles do not grow on a flight schedule. Build flexibility into accommodation and return travel.

    Embryos that continue developing may be biopsied and frozen while testing is performed. A frozen embryo transfer, if recommended, may take place in a later cycle.

    After you return home

    The clinic should provide records, medication instructions, emergency contacts and a follow-up plan. Your home clinician may need to coordinate early pregnancy monitoring or next-cycle preparation.

  • Understanding PGT-A results: euploid, aneuploid, mosaic and no result

    PGT-A reports can look definitive while still requiring careful interpretation. Result labels describe the tested sample and laboratory analysis; they are not a complete prediction of pregnancy or child health.

    Common categories

    A euploid result is consistent with the expected chromosome number in the sampled cells. An aneuploid result indicates a chromosome-number finding. A mosaic result suggests a mixture of cell findings, and a no-result report means the laboratory could not issue a conclusive result from that sample.

    Why clinic policy matters

    Clinics and laboratories may differ in reporting thresholds, terminology, re-biopsy policies and the circumstances in which mosaic embryo transfer is considered. Ask for the written policy before testing whenever possible.

    Counselling questions

    Complex results deserve a conversation with qualified professionals.

    • Which laboratory performed the test?
    • What platform and reporting thresholds were used?
    • How are segmental and mosaic findings reported?
    • What are the options for no-result embryos?
    • Is genetic counselling available before a transfer decision?