If you are considering PGT-M (preimplantation genetic testing for monogenic disorders) in Thailand, the cost is likely one of your first questions. While exact prices vary widely, understanding the components that make up the total cost can help you plan and compare options effectively. This guide explains the main cost factors, why quotes differ, and what to ask clinics before you commit.
At a Glance: Key Cost Components
- Probe development: A custom genetic test created for your specific condition.
- IVF cycle costs: PGT-M requires IVF to create embryos for testing.
- Embryo biopsy and testing: The laboratory work to remove and analyze cells from embryos.
- Medications and monitoring: Fertility drugs, blood tests, and ultrasounds.
- Additional services: Genetic counseling, shipping of samples, and storage fees.
Understanding PGT-M and Its Costs
PGT-M is a technique used during IVF to identify embryos that may carry a specific genetic disorder. Unlike PGT-A (which screens for chromosomal abnormalities) or PGT-SR (which checks for structural rearrangements), PGT-M is tailored to a single-gene condition. This customization is a major reason why costs can be higher and more variable.
Probe Development: The First Major Expense
Before any embryo can be tested, a laboratory must create a probe—a specialized test that detects the specific genetic mutation in your family. This process requires samples from you, your partner, and often other family members. The cost of probe development is usually a separate, one-time fee. It can take several weeks to complete, and the probe is then used for all embryos in your cycle.
Because each family’s genetic situation is unique, probe development costs are not standardized. Factors that may influence the price include the complexity of the genetic condition, the laboratory’s technology, and the number of family samples needed.
IVF Cycle Costs
PGT-M cannot be done without IVF, as embryos must be created in the laboratory. The IVF cycle itself includes ovarian stimulation, egg retrieval, fertilization, and embryo culture. These costs are typically bundled into a package, but the exact inclusions vary by clinic. Some packages may include medications, while others charge them separately.
Embryo Biopsy and Genetic Testing
Once embryos reach a certain stage (usually day 5 or 6), a few cells are removed in a process called biopsy. The cells are then sent to a genetic laboratory for analysis. This step involves both the biopsy procedure and the genetic testing itself. The testing fee may be per embryo or per cycle, and some clinics offer discounts for testing multiple embryos.
Medications and Monitoring
Fertility medications are a significant part of IVF costs. The type and dosage of drugs depend on your individual response to stimulation. Monitoring appointments, including blood tests and ultrasounds, are also necessary to track follicle development. These costs are often itemized separately.
Why Quotes Vary: What to Compare
When you request quotes from different clinics, you will notice that prices can differ substantially. This is not just about profit margins—it reflects differences in services, technology, and what is included. To make a fair comparison, ask each clinic for a detailed breakdown of costs, including:
- Probe development fees
- IVF cycle base cost
- Embryo biopsy and genetic testing fees
- Medication costs (and whether they are included)
- Monitoring and consultation fees
- Any additional charges for embryo freezing, storage, or shipping
Also ask whether the quote is in Thai baht or another currency, and whether it includes VAT. Some clinics may offer package deals that bundle multiple services, but ensure you understand what is not included.
Questions to Ask a Clinic
Before choosing a clinic for PGT-M, consider asking these questions:
- What is the total cost for a complete PGT-M cycle, including probe development and testing?
- Are medications included in the quote? If not, what is the estimated cost?
- How many embryos are included in the testing fee? What is the cost for additional embryos?
- What is the timeline for probe development and when will we know if it is successful?
- Are there any additional fees for genetic counseling, embryo storage, or shipping samples?
- What is the clinic’s policy on refunds if the cycle is canceled or no embryos are suitable for transfer?
Next Steps: Planning Your Budget
Once you have gathered quotes and asked the right questions, you can begin to plan your budget. Keep in mind that PGT-M is a complex procedure, and the cost is an investment in your family’s future. It is wise to set aside a contingency fund for unexpected expenses, such as additional testing or a second cycle.
If you are considering PGT-M in Thailand, take the time to research clinics thoroughly. Look for experience with your specific genetic condition, and ask about their laboratory partnerships and success rates—though remember that success rates are not a guarantee of outcome.
For more information on PGT in general, see our PGT in Thailand guide. If you have further questions, our FAQ section may help, or you can contact us for personalized assistance. You may also find our guides useful as you navigate your fertility journey.
Frequently asked questions
Why is PGT-M more expensive than PGT-A?
PGT-M requires a custom probe to detect a specific genetic mutation, which involves additional laboratory work and often family samples. PGT-A is a more standardized test for chromosomal abnormalities, so it does not require the same level of customization.
Does the cost of PGT-M include the IVF cycle?
Typically, PGT-M costs are separate from the IVF cycle, but some clinics offer packages that bundle both. Always ask for a detailed breakdown to understand what is included.
Are there any additional costs I should expect?
Yes, you may encounter costs for medications, monitoring, embryo storage, shipping of samples, and genetic counseling. Some clinics also charge for consultations or additional tests.
Can I use my own genetic counselor or laboratory?
Some clinics may allow you to work with an external genetic counselor or laboratory, but this can affect the overall cost and coordination. It is best to discuss this with the clinic directly.
Is PGT-M covered by insurance in Thailand?
Insurance coverage for PGT-M is rare and varies by policy. Most patients pay out of pocket. Check with your insurance provider to see if any part of the treatment is covered.
Continue your research
Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.